The Institute of Cell Therapy has significant achievements in the field of placental research, and has also developed effective methods for the isolation, cultivation and cryopreservation of stem cells, isolated from it. This allowed the Institute of Cell Therapy to be the first in Ukraine and one of the first in the world to offer future parents a high-tech service of the placenta storage after childbirth with the possibility of further biologics manufacturing and stem cells isolation for therapeutic purposes.
The achievements of the Institute of Cell Therapy scientists in the field of placentology are highly appreciated by the international scientific community. Thus, the scientific articles of the team of authors of the Institute of Cell Therapy, devoted to the study of placenta stem cells, were published in such prestigious international scientific journals as Placenta (2017, impact factor – 2.8), Experimental and Therapeutic Medicine (2016, 2017, impact factor – 1.56), Oncology letters (2018, impact factor – 1.6), Cytometry Part A (2018, impact factor – 3.26). The impact factor is an indicator that characterizes the status and importance (citation rate) of the publication.
In 2019, an article of the Institute of Cell Therapy on the results of a study on immunophenotype and gene expression of placenta stem cells at different stages of cultivation was accepted and published by the international peer-reviewed scientific journal BioMed Research International. This edition is cited in Scopus and Pubmed, the impact factor of the journal is 2.6. It should be noted that international peer-reviewed journals of such a high level publish only a small part of manuscripts, sent to the editor.
This paper of the group of Institute of Cell Therapy authors, called “High Proliferative Placenta-Derived Multipotent Cells Express Cytokeratin 7 at Low Level” has great practical significance, since presents valuable molecular markers of placental stem cells at different stages of cultivation, that is important for the purposes of cell therapy.